Coronary Artery Disease(CAD). Ischaemic heart diseases
Conditions
Interventions
Intervention 1: Intervention group: will receive two L carnitine 500 mg tablets (made in karen company) twice a day (with breakfast and dinner) for 12 weeks . Intervention 2: Control group: will recei
Treatment - Other
Treatment - Drugs
Intervention group: will receive two L carnitine 500 mg tablets (made in karen company) twice a day (with breakfast and dinner) for 12 weeks .
Control group: will receive quite similar tablets (in terms of shape and color and packaging. ..) containing soluble starch with the same dose and time-consuming
Sponsors
Vice Chancellor for research of Kermanshah University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients having at least 50% stenosis of one major coronary artery or receiving percutaneous transluminal coronary angioplasty (PTCA). Exclusion criteria: The patients with diabetes, liver, or renal diseases will be excluded. The patients under medications therapy, such as acenocoumarol, thyroid hormone, and warfarin, and those currently receiving vitamin supplements will also be excluded.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hs-CRP. Timepoint: before and after. Method of measurement: ELISA assay.;Myeloproxidase(MPO). Timepoint: before and after. Method of measurement: ELISA assay.;Nitrityrosine(NT). Timepoint: before and after. Method of measurement: ELISA assay.;Total antioxidant capacity(TAC). Timepoint: before and after. Method of measurement: Colorimetric assay.;Body composition. Timepoint: At first and the end of sixth and twelfth weeks of the study. Method of measurement: body Analyzers Jown Plus (Avis 333). | — |
Secondary
| Measure | Time frame |
|---|---|
| Evalution of patients diet. Timepoint: At first and the end of sixth and twelfth weeks. Method of measurement: 24 hour recall questionare.;The level of physical activity. Timepoint: at first and the end of sixth and twelfth weeks of study. Method of measurement: IPAQ questionare.;Blood pressure. Timepoint: at first and the end of study. Method of measurement: By mercury sphygmomanometer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryaam Shabanpur
Kermanshah University of Medical Science, School of Public Health
Outcome results
None listed