Chronic ulcer of skin, not elsewhere classified. Chronic ulcer of skin NOS
Conditions
Interventions
Intervention 1: Patients in intervention group will receive maggot debridement therapy in addition with routine treatment process for healing of diabetic foot ulcers. Intervention 2: Patients in contr
Treatment - Surgery
Patients in intervention group will receive maggot debridement therapy in addition with routine treatment process for healing of diabetic foot ulcers.
Patients in control group will receive routine healing process for healing of diabetic foot ulcers.
Sponsors
Vice Chancellor of Research, Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients with at least one diabetic foot ulcer, second degree (based on Wagner); Presence of at least one of two bacteria (Staphilococcus aureus and Pseudomonas aeruginosa) in the ulcers, patient's age between 30 to 80; At least seven week post ulceration; having ankle-brachial index (ABI) more than 0.6 or two clear beats on ulcerated leg; not need to be hospitalized; lack of other dangerous diseases; no need for anticoagulant or steroid pharmaceutics; ?not addicted to alcohol or opium; no entomophobia; to sign the consent. Exclusion criteria: Having sever diseases such as heart disorders and so on, Sever pain during maggot Therapy, Sever and un-controlled fever during maggot therapy, maceration around the wound after each interval of maggot therapy, Emergent hospitalization during or after of each interval of maggot therapy, Bleeding during maggot therapy
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ?acterial infections, Staphilococcus aureus and Pseudomonas aeruginosa. Timepoint: sampling before starting of the study and 48 and 96 hours after starting of the study. Method of measurement: culturing of samples in laboratory. | — |
Secondary
| Measure | Time frame |
|---|---|
| Amounts of wound secretions. Timepoint: 48 and 96 hours after starting of the study. Method of measurement: befors/after weighing of dressings of diabetic foot ulcers of both groups, treatment and control, synchronizingly. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Masud Yunesian
Tehran University of Medical Sciences
Outcome results
None listed