Skip to content

The effect of Oxytocin on Vaginal Atrophy and Sexual Function in Post-menopausal Women

The effect of Oxytocin Vaginal Gel on Vaginal Atrophy and Sexual Function in Post-menopausal Women

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160602028220N2
Enrollment
96
Registered
2018-02-09
Start date
2018-02-19
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vaginal atrophy and sexual function of postmenopausal women. Postmenopausal atrophic vaginitis

Interventions

Intervention 1: Intervention group: after the preparation of the oxytocin powder, by the trusted pharmacist Ahvaz University of Medical Sciences will be made oxytocin vaginal gel 400 IU and will be gi

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
40 Years to 60 Years

Inclusion criteria

Inclusion criteria: Have reading and writing skills Women aged 40-60 Passing for at least one year from the last menstruation or having a hormonal test with FSH of more than 40 international units The presence of vaginal atrophy Sexual performance score less than or equal to 26/5 Have sex and monogamy

Exclusion criteria

Exclusion criteria: vaginal infection Treatment with HRT or taking sex hormones during 8 weeks before study Any major disease genital Consuming Smoking, alcohol or any opiate Uterine bleeding and spotting Body mass index more than 30 Breast disease with unknown cause Use of vaginal drugs or any lubricant for at least 15 days before the study

Design outcomes

Primary

MeasureTime frame
Symptoms of vaginal atrophy. Timepoint: At the beginning of the intervention and 14 and 56 days after the start of the intervention. Method of measurement: The combined questionnaire vaginal atrophy symptoms.;The percentage of the maturity of the cells of the vagina. Timepoint: before and after intervention. Method of measurement: Vaginal smears.;The acidity of the vagina. Timepoint: before and after intervention. Method of measurement: PH strip.

Secondary

MeasureTime frame
Sexual function. Timepoint: before and after intervention. Method of measurement: Female sexual function index questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactIlnaz Zohrabi

Ahvaz University of Medical Sciences

zohrabi.i@ajums.ac.ir+98 61 3373 8331

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 27, 2026