The effect of propofol on isoflurane induced emergence agitation.

Comparing the effect of propofol and thiopental on emergence agitation after anesthesia with isoflurane in Children undergoing adenotonsillectomy surgery.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016060121383N6

Enrollment

Registered

2016-07-16

Start date

2016-05-24

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Emergent agitation. Restlessness and agitation

Interventions

Intervention 1: Administration Of propofol 2mg/kg. Intervention 2: Administration Of thiopental 5mg/kg.

Prevention

Administration Of propofol 2mg/kg

Administration Of thiopental 5mg/kg

Eligibility

Sex/Gender

All

Age

3 Years to 9 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: all patients aged 3 to 9 years who were scheduled for adenotonsillectomy surgeries under general anesthesia maintained by isoflurane. Exclusion criteria: all patients with history of allergic reactions to egg or soy beans; positive familial history of malignant hyperthermia; psychological disorders or any history of usage of sedative or hypnotic drugs; attention deficit hyperactivity disorder.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Agitation. Timepoint: 15, 30 minutes and 2, 4, 6 hours after surgery. Method of measurement: Modified Objective Pain Score (MOPS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Amir Saber Tanha

Birjand University of Medical Sciences

amirsaber63@gmail.com+98 56 3243 2778

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026