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The Effect of local Injection of Cortone on Pain preception after Root Canal treatment of teeth with Irreversible Pulpits

The Effect of local Injection of Cortone on Pain preception after Root Canal treatment of teeth with Irreversible Pulpits

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016053028173N2
Enrollment
213
Registered
2017-01-19
Start date
2016-08-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Teeth with irreversible pulpitis. Other and unspecified diseases of pulp and periapical tissues

Interventions

Intervention 1: Treatment of pain after root canal therapy of vital teeth with irreversible pulpitis using dexamethasone local injection in a double-blind study. Intervention 2: Treatment of pain afte
Treatment - Drugs
Placebo
Treatment of pain after root canal therapy of vital teeth with irreversible pulpitis using dexamethasone local injection in a double-blind study
Treatment of pain after root canal therapy of vital teeth with irreversible pulpitis using betamethasone L.A local injection in a double-blind study.
Treatment of pain after root canal therapy of vital teeth with irreversible pulpitis using placebo local injection in a double-blind study

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
9 Years to 85 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: All the teeth of maxillary and mandibular jaws diagnosed as irreversible pulpitis; with normal probing depth; tenderness; no history of using drugs such as analgesics (except ibuprofen), analgesic and anti-anxiety in the past two weeks; no medical history; no contraindication for prescribing cortisone; teeth with at least dilated periodontal ligament in periapical radiography; no dental implants in studied dental quadrant; approved vitality with pulp tests and cold spray; teeth with clinically diagnosed as irreversible pulpitis with response to electric pulp tester; longitudinal and magnified response (10 seconds); moderate to severe pain after the removal of the ice test cotton ball. Exclusion criteria: Systemic disease or maxillary sinusitis; unstable heart disease; high blood pressure; sensitivity to anesthetic lidocaine, epinephrine and latex; contraindications ofr lidocaine and epinephrine application; facial or oral paresthesia; use of any painkillers, Sedatives, anti-anxiety and corticosteroids during 2 weeks before treatment (except using 1.6 g of ibuprofen daily in past two days); pregnancy; breastfeeding; unreturnable teeth; teeth with full-coverage of restoration; over filling or over instrumentation during treatment; contraindications of using topical corticosteroids; diabetes; long-term steroid use; false positives vitality test observed after tooth necrosis; need to inject opal interpol for increasing the anesthesia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain relief. Timepoint: 6, 12, 24, 48, 72 hours and 7 days after injection. Method of measurement: Visual Analog Scale (VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHelen Jamlou

Faculty of Dentistry,Tabriz University of Medical Sciences

Dr.jamloo@yahoo+98 41 3335 5965

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026