Scaling effect on 2 salivary factors in patients with gingival inflammation

Evaluation Non-surgical treatment effect on Salivary Interleukin 6 and Interleukin 17 in patients with chronic periodontitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016053025649N5

Enrollment

Registered

2016-06-09

Start date

2016-02-04

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Periodontitis. Chronic periodontitis

Interventions

Intervention 1: Intervention group: scaling and root planning. Intervention 2: Control group: collecting saliva samples.

Treatment - Other

Intervention group: scaling and root planning

Control group: collecting saliva samples

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: good general health with no history of any systemic disease, no history of antibiotic therapy during 2 months before the study begins; no history of NSAID therapy. Exclusion criteria: smoking or alcohol abuse; patients with mucousal inflammatory lesions such as lichen planus or salivary glands disorders; pregnant or lactating females.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
IL-6. Timepoint: 1 month after scaling. Method of measurement: Mesured by specialized ELISA KIT.;IL-17. Timepoint: 1 month after scaling. Method of measurement: Mesured by specialized ELISA KIT.;Pocket depth. Timepoint: screening day , 1 month after scaling. Method of measurement: Mesuring the distance of pocket base to the gingival margin with periodontal probe.;Clinical attachment loss. Timepoint: screening day , 1 month after scaling. Method of measurement: Mesuring the distance of pocket base to the CEJ. Any changes in this normal amount is defined as clinical attachment loss.;Plaque index. Timepoint: screening day , 1 month after scaling. Method of measurement: colored surfaces of tooth by disclosing agent.;Bleeding on probing. Timepoint: screening day , 1 month after scaling. Method of measurement: Observe bleeding after probing.	—

Measure

Time frame

IL-6. Timepoint: 1 month after scaling. Method of measurement: Mesured by specialized ELISA KIT.;IL-17. Timepoint: 1 month after scaling. Method of measurement: Mesured by specialized ELISA KIT.;Pocket depth. Timepoint: screening day , 1 month after scaling. Method of measurement: Mesuring the distance of pocket base to the gingival margin with periodontal probe.;Clinical attachment loss. Timepoint: screening day , 1 month after scaling. Method of measurement: Mesuring the distance of pocket base to the CEJ. Any changes in this normal amount is defined as clinical attachment loss.;Plaque index. Timepoint: screening day , 1 month after scaling. Method of measurement: colored surfaces of tooth by disclosing agent.;Bleeding on probing. Timepoint: screening day , 1 month after scaling. Method of measurement: Observe bleeding after probing.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Masoome Eivazi

Kermanshah Dentistry School

m.eivazi@kums.ac.ir+98 83 3722 2400

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026