coronary arthery heart disease. Atherosclerotic heart disease
Conditions
Interventions
Intervention 1: Patients in Group A received five grams of vitamin C intravenously before induction of anesthesia and five grams of vitamin C in cardioplegia solution. Intervention 2: Group B is consi
Treatment - Drugs
Patients in Group A received five grams of vitamin C intravenously before induction of anesthesia and five grams of vitamin C in cardioplegia solution
Group B is considered as control group and received the same amount of a placebo.
Sponsors
Vice Chancellor for Research, Shiaz University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patients undergoing CABG, completed consent form. Exclusion criteria: history of preoperative arrhythmia; heart ejection fraction less than 30%; severe renal or hepatic failure; pacemaker, permanent or temporary, treatment with anti-arrhythmic drugs and digoxin; some degree of AV block or bradycardia with a heart rate less than 50 min; a history of recent myocardial infarction (less than one month); high initial troponin levels (> 0.3 macro gram per liter), re-operation (redo) or complex (valve replacement + CABG).
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the serum levels of CPK-MB, Troponin I, LDH. Timepoint: at the induction, termination of cardiopulmonary bypass, 6 hours after the procedure, 24 hours of operation. Method of measurement: Arterial blood samples. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNafiseh Emadi
Shiraz University of Medical Sciences
Outcome results
None listed