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Efficacy and side effects of risperidone, quetiapine and olanzapine in the treatment of Shisheh psychosis

Comparison of the effects and side effects of the three drugs risperidone, quetiapine and olanzapine in the treatment of psychosis symptoms due to Shisheh

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160530028173N5
Enrollment
45
Registered
2023-12-12
Start date
2023-11-22
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

psychosis symptoms due to Shisheh. Other stimulant related disorders

Interventions

Intervention 1: Patients will receive risperidone from Sobhan company daily in the therapeutic range of 2 to 8 mg. The patient will be evaluated by demographic questionnaire, urine test, PANSS positiv

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Having criteria for glass-induced psychosis disorder based on DSM-5 (through clinical interview by psychiatrist). Treated with one of the antipsychotics risperidone, quetiapine and olanzapine No other psychiatric disorders Willingness of an individual or family (conscious consent) to participate in the study Minimum age 18 If you have a history of drug treatment for the above disorder, at least three weeks have passed since you stopped taking the drug

Exclusion criteria

Exclusion criteria: History of mental disorders History of epilepsy History of brain trauma Taking drugs other than target group treatment drugs Unwillingness of the patient or the family to continue cooperating in the study for any reason Incomplete questionnaires If a sample has other psychiatric disorders, including personality disorders, it will be excluded from the plan and will continue its routine treatment. Incidence of drug complications based on the AIMS scale

Design outcomes

Primary

MeasureTime frame
Positive Symptoms Severity. Timepoint: Before the intervention, one month after the intervention. Method of measurement: PANSS positive and negative symptom scale.;Negative Symptoms Severity. Timepoint: Before the intervention, one month after the intervention. Method of measurement: PANSS positive and negative symptom scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactArash Mohagheghi

Tabriz University of Medical Sciences

mohaggheghi.a@gmail.com+98 41 3380 4486

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026