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Evaluating the effect of adding dexamethasone to lidocaine in improving the quality of the upper extremity anesthesia through venous injection (Bier's Block) in orthopedic operations

A clinical trial of comparing dexamethasone plus lidocaine with lidocaine alone on the quality of Bier's Block in orthopedic patients for upper extremity surgeries

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016052928158N1
Enrollment
100
Registered
2017-05-17
Start date
2016-06-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intravenous regional anesthesia. Injuries to the wrist and hand AND Injuries to the elbow and forearm

Interventions

Intervention 1: A double tourniquet was fastened over the arm of the extremity which needed surgery. In the control group local anesthetic solution, 3mg/kg lidocaine with distilled water up to a volum
Treatment - Drugs
Treatment - Other
A double tourniquet was fastened over the arm of the extremity which needed surgery. In the control group local anesthetic solution, 3mg/kg lidocaine with distilled water up to a volume of 40 cc was i
A double tourniquet was fastened over the arm of the extremity which needed surgery. In the study group local anesthetic solution, 3 mg/kg lidocaine and 8 mg dexamethasone with distilled water up to a

Sponsors

Vice chancellor for research, Hormozgan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: ASA class I-II, 15 to 65 years old, upper limb injuries distal to the elbow. Exclusion criteria: Muscle-nerve-skin diseases, allergic reactions, general anesthesia requirement due to inadequate regional anesthesia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Sensory block onset. Timepoint: 30 seconds. Method of measurement: Pinprick test (needle 22 gauge bevel).;Sensory block recovery. Timepoint: 30 seconds. Method of measurement: pinprick test (with needle 22 gauge bevel).;Time to first request of analgesic in recovery. Timepoint: 15, 30, 45, and 60 minutes after intervention. Method of measurement: minutes.;Intraoperative opium consumption. Timepoint: 1 hours. Method of measurement: Total fentanyl consumption dose (micro-gram).;Patients satisfaction. Timepoint: 1 hours. Method of measurement: Excellent: if there is no complain during operation. Good: if there is mild discomfort but without the need of analgesia during operation. Moderate: if the patient has discomfort and needs analgesia. Poor: If the patient receives 2 doses of fentanyl (1 microgram/kg) but still has discomfort, and requires sedative doses of propofol (25-75 microgram/kg/min) to tolerate the procedure.

Secondary

MeasureTime frame
Systolic blood pressure. Timepoint: Baseline, 5 minutes after tourniquet inflation, 20 minutes after tourniquet inflation, immediately after tourniquet deflation, in recovery. Method of measurement: Non-invasive automatic blood pressure monitoring device.;Diastolic blood presure. Timepoint: Baseline, 5 minutes after tourniquet inflation, 20 minutes after tourniquet inflation, immediately after tourniquet deflation, in recovery. Method of measurement: Non-invasive automatic blood pressure monitoring device.;Mean arterial blood pressure. Timepoint: Baseline, 5 minutes after tourniquet inflation, 20 minutes after tourniquet inflation, immediately after tourniquet deflation, in recovery. Method of measurement: Non-invasive automatic blood pressure monitoring device.;Heart rate. Timepoint: Baseline, 5 minutes after tourniquet inflation, 20 minutes after tourniquet inflation, immediately after tourniquet deflation, in recovery. Method of measurement: Beats per minute by an electrocardiographic monitoring device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Manuchehr Kamali

Hormozgan University of Medical Sciences

manuchehr.kamali@yahoo.com+98 76 3334 7001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 6, 2026