Stable Chronic Angina. Angina pectoris with documented spasm
Conditions
Interventions
Intervention 1: Case group receives 3 gram mellisa suplement daily (1 capsule contains 1 gram mellisa after each meal)
during two months. Intervention 2: Control group receives 3 gram corn starch pow
Treatment - Drugs
Case group receives 3 gram mellisa suplement daily (1 capsule contains 1 gram mellisa after each meal)
during two months
Control group receives 3 gram corn starch powder (1 capsule contains 1 gram corn starch powder after each meal) during two months
Sponsors
Research Assistance, Ahvaz Jondishapour University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: suffering from chronic stabe angina; age 40-75 yr; BMI 18.5-40; willing to co-operate Exclusion criteria: suffering from hypertension; diabete; aritmia; kidney disease;liver disease;blood disease; pulmunary disease; mascuskeletal diseas; artrit rhematism; inflammatory bowel disease; digestive disease; tyroid disorders; athletes; pregnants and lactating women; women who are willing to be pregnant; being on special diets such as vegetarianism; history of mellisa allergy; consumption of nutritional supplements, sedatives, smoking, alchohol; change in type or amount of medications, diet, and physical activity during the study; patients who suffer from complications such as headache, dizzines, nasia, and mellisa intolerance during the study; not willing to continue co-operation with the study
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lipid Profile. Timepoint: before intervention- at the end of intervention. Method of measurement: Blood Analysis. | — |
Secondary
| Measure | Time frame |
|---|---|
| LDH. Timepoint: before intervention- at the end of intervention. Method of measurement: blood analysis.;Hs-CRP. Timepoint: before intervention- at the end of intervention. Method of measurement: blood analysis.;Sleep disorder. Timepoint: before intervention- at the end of intervention. Method of measurement: Pittsburg sleep disorder questionnaire.;Depression. Timepoint: before intervention- at the end of intervention. Method of measurement: Depression Anxiety Stress Scales (DASS).;Anxiety. Timepoint: before intervention- at the end of intervention. Method of measurement: Depression Anxiety Stress Scales (DASS).;Stress. Timepoint: before intervention- at the end of intervention. Method of measurement: Depression Anxiety Stress Scales (DASS).;Heart functional capacity. Timepoint: before intervention- at the end of intervention. Method of measurement: exercise test.;Ejection Fraction. Timepoint: before intervention- at the end of intervention. Method of measurement: echocardiography.;MDA. Timepoint: before intervention- at the end of intervention. Method of measurement: blood analysis.;NO. Timepoint: before intervention- at the end of intervention. Method of measurement: blood analysis.;Paraoxonase 1. Timepoint: before intervention- at the end of intervention. Method of measurement: blood analysis. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contact?Assieh Mohammadzadeh
Ahvaz Jondishapour University of Medical Sciences
Outcome results
None listed