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Effects of Botanical mouthwash of Aloe Vera on ventilator associated pneumonia of patients having Endotracheal tube hospitalized in the Intensive Care Unit

Effects of Botanical mouthwash of Aloe Vera on ventilator associated pneumonia of patients having Endotracheal tube hospitalized in the Intensive Care Unit

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016052828134N1
Enrollment
79
Registered
2016-06-21
Start date
2016-01-30
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Pneumonia. Condition 2: dental plaque. Condition 3: dental plaque. Influenza and pneumonia Deposits [accretions] on teeth Caries of dentine

Interventions

Intervention 1: intervention group: Using 15 ml of Aloe Vera mouthwash, every 12 hours, for 4 days. Intervention 2: Control group: Using 15 ml of normal saline, every 12 hours, for 4 days.
Treatment - Drugs
intervention group: Using 15 ml of Aloe Vera mouthwash, every 12 hours, for 4 days.
Control group: Using 15 ml of normal saline, every 12 hours, for 4 days.

Sponsors

Research Deputy of Shahid Beheshti university of medical sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: 18-65 years old; having endotracheal tube through the mouth; admitted to ICU less than 12 hours; having natural teeth;don't have history of use antibiotic two weeks ago; don't have pregnancy and no history of allergy to herbal compounds;don't have HIV and use of steroid drugs; not have an injury in the mouth and around it;not have pneumonia;don't have history of use antibiotic on two weeks ago;don't have leukopenia and noutropenia and serum albumin 6 score of clinical pulmonary infection score on 12 hours first time admission

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pneumonia. Timepoint: Immediately before intervention and four days later. Method of measurement: Modified clinical pulmonary infection score.

Secondary

MeasureTime frame
Dental plaque index. Timepoint: Immediately before intervention and four days later. Method of measurement: o'leary plaque index.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNasrin Mirbastegan

Shahid Beheshti university of medical sciences

mirbastegan.nasrin@gmail.com+98 21 8865 5366

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026