Skip to content

Sildenafil and fetal heart rate

The effect of sildenafil on fetal heart rate patterns during labor in primiparous pregnant women

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160524028038N19
Enrollment
100
Registered
2024-02-27
Start date
2024-04-04
Completion date
Unknown
Last updated
2024-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fetal heart rate during labor. Abnormality in fetal heart rate and rhythm complicating labor and delivery

Interventions

Intervention 1: Intervention group: In addition to induction and routine interventions during labor, they will receive oral sildenafil at a dose of 50 mg every 8 hours up to a maximum of 150 mg, the f

Sponsors

Yasouj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: First and term pregnancy (gestational age over 37 weeks) Absence of pre-eclampsia, hypertension and gestational diabetes and absence of underlying disease in the mother Not getting magnesium sulfate Absence of fetal growth restriction, polyhydramnios and oligohydramnios of the fetus Absence of prolonged rapture of membrane (more than 12 hours) singleton pregnancy Absence of structural abnormalities Cephalic display Candidate for vaginal delivery Cervical dilatation less than 4 cm at the time of admission candidate for induction

Exclusion criteria

Exclusion criteria: Dissatisfaction of the mother

Design outcomes

Primary

MeasureTime frame
Fetal heart rate patterns. Timepoint: Continuous fetal heart rate monitoring. Method of measurement: In this study, the normal fetal heart rate pattern based on the standard protocol means a heart rate between 110-160 beats per minute and a beat-to-beat variability of 5-25 beats per minute during labor and the pathological fetal heart rate pattern means a late deceleration in heart rate relative to to uterine contractions, early deceleration means a decrease in heart rate at the same time as uterine contractions, variable deceleration means a decrease in heart rate unrelated to uterine contractions, prolong deceleration means a deceleration in heart rate of more than 2 minutes in 10 minutes of continuous heart rate monitoring, tachycardia means a heart rate of more than 160 and bradycardia means a heart rate of less than 110 and reduced variability means changes of less than 5 beats per minute.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Asadi

Yasouj University of Medical Sciences

zasadik66@gmail.com+98 917 793 1581

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026