Female infertility due to poor ovarian response. Female infertility of other origin
Conditions
Interventions
Intervention 1: Intervention group A: Sildenafil (sildenafil citrate 25 mg daily
Visarsin) starting from the first day of the cycle until the day of egg retrieval) along with Inofolic (Inofolic powder 4 grams daily) starting from the first day of the previous cycle for 40 days. In
Razak Pharmaceutical Company, Iran) starting from the first day of the cycle until the day of egg retrieval along with inofolic (inofolic powder 4 grams daily) starting from the first day of the previ
Visarsin) starting from the first day of the cycle until the day of egg retrieval with inofolic (inofolic powder 4 grams daily) starting from the first day of the previous cycle for 40 days. Intervent
Sponsors
Bandare-abbas University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Aged 18 to 45 years Not using other vasodilator drugs such as nitric oxide and calcium channel blockers Normal semen analysis Poor ovarian response
Exclusion criteria
Exclusion criteria: Patients with other endocrine disorders such as hyperprolactinemia, PCOS, etc. History of ovarian surgery or ovarian endometrioma Smoker Cardiovascular disorders Unwillingness to cooperate Sildenafil sensitivity and intolerance to side effects (hot flashes, vision disorders, severe drop in blood pressure and hearing disorders)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oocyte Quality. Timepoint: 2-3 hrs. after oocyte collection. Method of measurement: Microscopic Evaluation.;Number of retried oocyte. Timepoint: On day of oocyte retrieval. Method of measurement: Counting number of total oocytes with microscope.;Number of embryo. Timepoint: On the 2nd day after ICSI. Method of measurement: Observation with microscope. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Azizi
Bandare-abbas University of Medical Sciences
Outcome results
None listed