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Lactofem and sexual function

Evaluating the effect of Lactofem supplementation on sexual performance of women with depression compared to antidepressant treatment alone

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160524028038N14
Enrollment
104
Registered
2022-12-19
Start date
2022-12-11
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression. Major depressive disorder, single episode

Interventions

Intervention 1: Intervention group: Selective serotonin reuptake inhibitor (SSRI) antidepressants plus one Lactofem capsule (including Lactobacillus acidophilus 109 ? 2, Bifidobacterium bifidus 109 ?

Sponsors

Yasouj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Age 18-45 years Reading and writing literacy Obtaining a score of less than twenty and diagnosing mild to moderate depression on the Hamilton scale For at least 4 weeks, be treated with anti-depressants that affect sexual function Marriage Having sex at least once a month Having an emotionally satisfying relationship with a stable and sexually active spouse for at least one year Desire to participation

Exclusion criteria

Exclusion criteria: The unwillingness of the research unit during sampling, which will lead to his withdrawal from the study Having speech or hearing problems Addiction to drugs and alcohol in a person or his spouse Getting women's diseases and vaginitis and sexual disorders with organic background according to the statement of the research unit Sexual problem before taking antidepressants symptoms of psychosis Loss of relatives, acquaintances or friends during the last six months Known sexual problem in men Current pregnancy and breastfeeding Suffering from internal diseases such as cardiovascular, thyroid, arthritis, diabetes, epilepsy, kidney infection Taking birth control pills Taking drugs that affect sexual performance, such as blood pressure reducers, antihistamine H2 blockers, barbiturates).

Design outcomes

Primary

MeasureTime frame
Sexual function. Timepoint: Before the intervention and three months after the intervention. Method of measurement: Female sexual function index.;Depression severity. Timepoint: Before the intervention and three months after the intervention. Method of measurement: Beck depression questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRaana Moshtaghi

Yasouj University of Medical Sciences

moshtaghi.raana@gmail.com+98 74 3333 7251

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026