polycystic ovarian syndrome. Polycystic ovarian syndrome
Conditions
Interventions
Intervention 1: Intervention group: Sildenafil (sildenafil citrate (Vizarcin) 25 mg daily) + metformin tablets (500 mg three times a day orally). Intervention 2: Intervention group: melatonin (3 mg of
Sponsors
Yasouj University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Patients aged 18 to 45 years Body mass index 19-25 Confirmation of polycystic ovary syndrome based on the Rotterdam criteria
Exclusion criteria
Exclusion criteria: Patients who do not want to cooperate. Sildenafil sensitivity and intolerance to side effects (hot flashes, vision disorders, severe drop in blood pressure and hearing disorders) pregnancy Taking ocp or ovulation stimulation drugs Existence of severe mental conditions since 6 months before the research, which has an adverse effect on the patient's quality of life Suffering from a severe degree of depression and anxiety according to the depression and anxiety questionnaire based on the Beck depression and anxiety questionnaire Current use of psychiatric medications Language or cognitive problems preventing the patient from completing the questionnaire smoking Current use of drugs affecting sexual performance Previous diagnosis of an organic cause for sexual dysfunction by an experienced physician Taking vasodilator drugs and drugs that interact with metformin, sildenafil, and melatonin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sexual function. Timepoint: Before the intervention and three after the intervention. Method of measurement: FSFI sexual function questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSadaf Abbasi
Yasouj University of Medical Sciences
Outcome results
None listed