Cervical insufficiency. Pregnancy with abortive outcome
Conditions
Interventions
Intervention 1: Intervention group(cerclage plus lactofem): Lactofem capsule (500 mg) made by Iranian zist-takhmir Company will be administered orally and daily from the day of cerclage until the end
Sponsors
Yasouj University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Patient age 18-45 years Gestational age between 14-24 weeks Cerclage by McDonald method Absence of syphilis, gonorrhea and HIV clinically Single pregnancy Lack of maternal insulin-dependent diabetes mellitus, treatment of hypertension, lupus No clinical chorioamnionitis
Exclusion criteria
Exclusion criteria: Reluctance to participate in the study Failure to complete the course of treatment or use of probiotics Taking drugs that affect the intestinal microbial flora, such as antibiotics Occurrence of any genital or urinary tract infection requires antibiotic treatment during treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Premature preterm birth (less than 34 weeks gestation). Timepoint: End of intervention. Method of measurement: Questionnaire.;Late preterm birth (34-37 weeks gestation). Timepoint: End of intervention. Method of measurement: Questionnaire.;Premature rupture of amniotic sac,. Timepoint: End of intervention. Method of measurement: Questionnaire.;Type of delivery (normal and cesarean section). Timepoint: End of intervention. Method of measurement: Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRaziyeh Vanda
Yasouj University of Medical Sciences
Outcome results
None listed