Intra echal Opioid Induced Pruritus. Other complications of spinal and epidural anaesthesia during labour and delivery
Conditions
Interventions
Intervention 1: Intervention 1: before performing intratechal opioid injection, 2cc Ondansetrone was injected intravenously. Intervention 2: Control group: before performing intratechal opioid, 2cc di
Treatment - Drugs
Placebo
Intervention 1: before performing intratechal opioid injection, 2cc Ondansetrone was injected intravenously
Control group: before performing intratechal opioid, 2cc disttiled water was injected intravenously
Intervention 2: before prforming Iintra techal opioid injection, 2cc Dexamethasone was injected intravenously.
Sponsors
Vice chancellor for Research and Technology, Hamadan University Of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: parturient aged 18-45 and ASA I with gestational age 36-42 weeks that candidates for labor under regional analgesia. Exclusion criteria: preeclampsia; chronic hypertension; diabetes mellitus; allergy to drugs in the study; contraindication of neuraxial anesthesia; mother addiction and drug abuse and any unexpected accident that need for cesarean section; previous history of itching and allergy.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intratechal opioid induced pruritus. Timepoint: just after spinal anesthesia, 5, 10, 15 min later then every 15 mint to 90 min. Method of measurement: Pruritus was asses by observe the scraching and by Visual Analouge Scale of pruritus every 5 Minute for 15 minute and every 15 mnutes untile 90 min. | — |
Secondary
| Measure | Time frame |
|---|---|
| Other complication of spinal anesthesia: nausea & vomitting, hypotension. Timepoint: After spinal anesthesia untile the end of labor or to 90 min after spinal anesthesia. Method of measurement: Blood pressure was measured with automatic blood pressure device and hypotension was defined as more than 20% decrease of BP compared to baseline, and observation of any retching or explosion Of gastric content. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactPouran Hajian M.D
Endometrium and Emdometriosis Research Center
Outcome results
None listed