Skip to content

Effect of Citiculin on Cognitive Complications in Bipolar Patients in manic episode Receiving Electroconvulsive

Effect of Citiculin on Cognitive Complications in Bipolar Patients in manic episode Receiving Electroconvulsive therapy (ECT)

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160523028008N9
Enrollment
60
Registered
2021-02-03
Start date
2021-02-19
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bipolar Disorder, current episode manic severe with psychotic features. Bipolar Disorder, current episode manic severe with psychotic features

Interventions

Intervention 1: Intervention group: Thirty patients with bipolar disorder in the mania phase are treated with a single 250 mg intramuscular dose of citicoline before the intervention, the third and fi

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Bipolar patients in the acute phase of mania who, according to the physician, needed ECT Young Mania Rating Scale greater than or equal to 20 Age greater than or equal to 18

Exclusion criteria

Exclusion criteria: Psychiatric disorders except Bipolar 1 Disorder Having a systemic disease Citicolin Contraindication

Design outcomes

Primary

MeasureTime frame
Cognitive function. Timepoint: Before the intervention, after the first, second, third and fifth sessions of ECT. Method of measurement: Cognitive function Test by using Minimal Mental State Exam (MMSE).

Secondary

MeasureTime frame
The reduction of mania symptoms. Timepoint: At the start of the study and the first and second week after receiving citicolin. Method of measurement: Young Mania Rating Scale (YMRS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLila Jahangard

Hamedan University of Medical Sciences

Jahangard_Li@yahoo.com+98 81182851015

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026