Effect of inositol on CRP and IVF outcomes in patients with polycystic ovary syndrome

Investigation of the effect of inositol on CRP and IVF outcomes in patients with polycystic ovary syndrome

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160523028008N34

Enrollment

114

Registered

2025-03-02

Start date

2025-03-09

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovary syndrome. Polycystic ovarian syndrome

Interventions

Intervention 1: Intervention group: Myo-inositol 2000 mg + Metformin 1500 mg daily for two months. Intervention 2: Control group: Metformin 1500 mg daily for two months.

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Women with polycystic ovary syndrome (PCOS) based on Rotterdam criteria are candidates for IVF. Age 18-40 years. Female infertility factor.

Exclusion criteria

Exclusion criteria: Severe endometriosis Drug allergy Any acute or chronic disease affecting CRP(C-reactive protein) levels

Design outcomes

Primary

Measure	Time frame
Hs-CRP. Timepoint: At the beginning of the study and after 8 weeks of intervention. Method of measurement: Elisa kit.;Embryo quality. Timepoint: 2 days after embryo transfer. Method of measurement: Diagnosed by Embryologist and with embryological criteria.;Ovum grade. Timepoint: 2months after intervention. Method of measurement: A -D observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShamim Pilehvari

Hamedan University of Medical Sciences

sh.heidari2016@yahoo.com+98 938 567 7741

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026