Skip to content

The Determining the effect of vaginal probiotics on perinatal outcomes

The Determining the effect of vaginal probiotics on perinatal outcomes in women with premature rupture of membranes

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160523028008N30
Enrollment
106
Registered
2024-01-17
Start date
2024-01-20
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preterm spontaneous labour with term delivery. Preterm spontaneous labour with term delivery

Interventions

Intervention 1: Intervention group: Women with premature rupture of membranes are prescribed intravenous ampicillin 2 grams every 6 hours and then 500 milligrams of amoxicillin capsules every 8 hours

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Single live pregnancy Gestational age between 24 and 34 weeks with premature rupture of fetal membranes No evidence of fetal distress No vaginal bleeding No symptoms of chorioamnionitis

Exclusion criteria

Exclusion criteria: Active labor Symptoms of vaginal infection Fetal congenital abnormalities, individuals who give birth within the first 48 hours of hospitalization. High blood pressure Diabetes Fetal growth restriction, and fetal

Design outcomes

Primary

MeasureTime frame
Gestational age. Timepoint: Delivery time. Method of measurement: By the date of the first day of the last period and ultrasound.;The time interval between the rupture of the membranes and the onset of labor. Timepoint: Delivery time. Method of measurement: The length of delay per day is calculated by subtracting the delivery time from the membrane rupture time.

Secondary

MeasureTime frame
Birth weight. Timepoint: post partum. Method of measurement: Using a digital scale.;Apgar score. Timepoint: after delivery. Method of measurement: documented data.;Chorioamnionitis. Timepoint: after delivery. Method of measurement: documented data (will be determined by clinical symptoms, including fever and tachycardia).;Neonatal sepsis. Timepoint: after delivery. Method of measurement: documented data( by blood culture).;Type delivery. Timepoint: after delivery. Method of measurement: Cesarean section - vaginal normal delivery.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamidhe Parsapour

Hamedan University of Medical Sciences

h.parsapour@umsha.ac.ir+98 81 3838 0717

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026