Convulsions of newborn. Convulsions of newborn
Conditions
Interventions
Intervention 1: Intervention group: Patients are treated with levetiracetam injection (500 mg / 5ml by Estragen Company, Switzerland) at a loading dose of 50 mg/kg and infusion rate of 2 mg/kg/min (wi
Sponsors
Hamedan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Days to 28 Days
Inclusion criteria
Inclusion criteria: Gestational age of 36 weeks or more Weighing 2 kg or more Occurrence of neonatal seizures between the first day and the 28th day after birth Consent of the baby's parents or legal guardian
Exclusion criteria
Exclusion criteria: Receiving anti convulsion drugs in the last 72 hours Seizures due to hypocalcemia, hypoglycemia, hypomagnesemia, and other electrolyte disorders Serum creatinine level greater than 1.6 mg / dL
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete cessation of seizures for 24 hours after medication. Timepoint: In the first 24 hours after medication. Method of measurement: Stopping seizure movements clinically (clinical assessment).;Number of doses received to stop seizures. Timepoint: In the first 24 hours after medication. Method of measurement: Patient medical record. | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduce irritability. Timepoint: Before and after intervention. Method of measurement: Daily clinical examination and parental observations.;Reduce anorexia. Timepoint: Before and after intervention. Method of measurement: Daily clinical examination and parental observations. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNader Faraji
Hamedan University of Medical Sciences
Outcome results
None listed