Skip to content

Probiobitcs effect in pediatric migraine

Analysis of probiobitcs effect in pediatric migraine prophylaxis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160523028008N22
Enrollment
32
Registered
2022-03-05
Start date
2022-02-20
Completion date
Unknown
Last updated
2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine. Migraine

Interventions

Intervention 1: Intervention group: Consumption of propranolol (Tolid Daroo, Pharmaceutical) with dosage 1 mg/kg divided into 2 doses along 250 mg Yumogi capsule from Yomogi company for 2 months. Inte

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 15 Years

Inclusion criteria

Inclusion criteria: Children aged 5 to 15 years A definitive diagnosis of migraine disease by a neurologist Family consent to attend the project Suitable for the onset of migraine prophylaxis: (leading to school absenteeism or dysfunction, PEDMIDAS of more than 20)

Exclusion criteria

Exclusion criteria: Other types of headaches, including chronic or drug-related headaches Inflammatory bowel disease Having neurological disorders Use of antibiotics for 2 months before the start of the study Use of probiotic supplements 2 weeks before the start of the study. Prohibition of propranolol in patients such as asthma and diabetes.

Design outcomes

Primary

MeasureTime frame
Monthly frequency of headache. Timepoint: Before and two months after treatment. Method of measurement: Asking from patient.;Severity of headache. Timepoint: Before and two months after treatment. Method of measurement: Asking from patient.;Pediatric Migraine Disability score. Timepoint: Before and two months after treatment. Method of measurement: Asking from patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBentolhoda Keshtkar Sohi

Hamedan University of Medical Sciences

Hodakeshtka86@gmail.com+98 81 3264 0064

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026