Effect of intraperitoneal and intravenous dexamethasone in reduce pain and nausea and vomiting after laparoscopic surgery

The effect of intra peritoneal and intravenous dexamethasone in reduce pain and nausea and vomiting after gynecology laparoscopic surgery.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160523028008N18

Enrollment

Registered

2021-09-30

Start date

2021-11-01

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic surgical. Laparoscopic surgical procedure converted to open procedure

Interventions

Intervention 1: Intervention group: 8 mg dexamethasone (2 CC) intravenously injected. and 2 CC normal saline peritoneal cavity after surgery and before leaving the trocar was sprayed. Intervention 2

Eligibility

Sex/Gender

Female

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Ages between 18 and 60 years Patients who need laparoscopic surgery due to a gynecological indication

Exclusion criteria

Exclusion criteria: History of abdominal surgery Extensive pelvic surgeries Body mass index(BMI) of more than 40 Existence of diseases of the stomach and intestines Drug allergy to dexamethasone

Design outcomes

Primary

Measure	Time frame
Severity of nausea. Timepoint: 6, 12, 18 and 24 hours after surgery. Method of measurement: Visual Analogue Scale (VAS).;Severity of vomiting. Timepoint: 6, 12, 18 and 24 hours after surgery. Method of measurement: Visual Analogue Scale (VAS).;Severity of pain. Timepoint: 6, 12, 18 and 24 hours after surgery. Method of measurement: Visual Analogue Scale (VAS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzadeh Akbari sene

Iran University of Medical Sciences

akbarisene@aiums.ac.ir+98 21 6655 2972

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026