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Evaluation of the effectiveness of doxycycline in the treatment of outpatients with Covid-19

Evaluation of the effectiveness of doxycycline in the treatment of outpatients with Covid-19 .

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160523028008N16
Enrollment
88
Registered
2021-08-25
Start date
2021-10-02
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19, virus identified. COVID-19

Interventions

Intervention 1: Intervention group: Doxycycline capsules are given orally made by Iran Daru Company (Iran) 100 mg twice a day for 10 days along with standard care and medication measures for Covid pat

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Minimum age 18 and maximum age 80 years Do not take doxycycline for the last five days Patients with definitive diagnosis of Covid 19 (RT-PCR) candidate for outpatient treatment with pulmonary involvement score on CT scan equal to or below 8 Patients suspected of Covid-19 based on clinical signs and manifestations of CT scan and laboratory results candidate for outpatient treatment.

Exclusion criteria

Exclusion criteria: Hospitalization Patients with no indications for outpatient treatment based on national protocol. pregnancy Patients with a history of allergic reaction or Doxycycline. Underlying disease

Design outcomes

Primary

MeasureTime frame
Improvement of clinical symptoms. Timepoint: Start of study and 3, 7, 14 days after study. Method of measurement: Questionnaire - telephone follow-up and.;Hospitalizations. Timepoint: 7 and 14 days after study. Method of measurement: Telephone follow up.;Mortality rate. Timepoint: 7 and 14 days after study. Method of measurement: Telephone follow up.

Secondary

MeasureTime frame
Side effects of doxycycline. Timepoint: 7 and 14 days after study. Method of measurement: Telephone follow up.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid Sadeghibidar

Hamedan University of Medical Sciences

hamid.sadeghibidar@gmail.com+98 81 3838 0283

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026