Medical abortion. Complication following abortion and ectopic and molar pregnancy,unspecified
Conditions
Interventions
Intervention 1: Intervention group: Letrozole 10 mg and misoprostol tablets 800 mg three doses at intervals of three hours vaginal made by Abureyhan Pharmaceutical Company, Iran. Intervention 2: Inter
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age older than 18 years Gestational age based on ultrasound findings less than 12 weeks Patient and spouse satisfaction Lack of systemic diseases such as hypertension, kidney disease Hemoglobin greater than or equal to 10 g / l, diastolic blood pressure less than 95 mm Hg
Exclusion criteria
Exclusion criteria: Having an IUD Any allergy to letrozole or misoprostol Liver disease, kidney failure, high blood pressure and asthma Convulsions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The interval between induction and abortion beginning and opening of cervical internal os. Timepoint: Until 24 hours after receiving Misoprostol, every 1 hou. Method of measurement: Sonography.;The interval between induction and complete abortion. Timepoint: Until 24 hours after receiving Misoprostol, every 1 hour. Method of measurement: Sonography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Gastrointestinal problems (nausea or vomiting). Timepoint: From receiving Letrozole until 24 hours after receiving Misoprostol. Method of measurement: Objective. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMojgan Mokhtari
Iran University of Medical Sciences
Outcome results
None listed