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Transcranial Magnetic Stimulation ( rTMS ) add-on therapy to Standard treatment in Multiple sclerosis Patients with Depression Symptoms

Effectiveness of Repetitive Transcranial Magnetic Stimulation ( rTMS ) add-on therapy to Standard treatment in Multiple sclerosis Patients with Depression Symptoms in Sina Farshchian Hospital in Hamadan city

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160523028008N11
Enrollment
40
Registered
2021-02-20
Start date
2021-04-21
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis. Demyelinating diseases of the central nervous system

Interventions

Intervention 1: Intervention group: 10 session of 20 minute of trans cranial direct current stimulation by 2 ma. Intervention 2: Control group: 10 inactive session of 20 minutes by the same deviceCate

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Satisfaction to participate in the study Patient with multiple sclerosis of any type and with moderate and high depression Not receive repeated transcranial magnetic stimulation and electroconvulsive therapy in the past two months

Exclusion criteria

Exclusion criteria: Having a shunt and any other metal object near the head Interferon consumption Pregnant or lactating women Patients at risk of suicide Patients with other psychiatric disorders such as bipolar disorder

Design outcomes

Primary

MeasureTime frame
Depression rate. Timepoint: before and after 10 sessions of intervention. Method of measurement: Montgomery-Asberg Depression Rating Scale (MADRS).;Fatigue severity test. Timepoint: before and after 10 sessions of intervention. Method of measurement: Fatigue Severity Scale.;Expanded Disability Status Scale. Timepoint: before and after 10 sessions of intervention. Method of measurement: Expanded Disability Status Scale.;Cognitive Assessment. Timepoint: before and after 10 sessions of intervention. Method of measurement: Montreal Cognitive Assessment.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Keshavarzi

Hamedan University of Medical Sciences

drkeshavarzi@yahoo.com+98 81182851015

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026