Pneumonia. Pneumonia, unspecified
Conditions
Interventions
Intervention 1: In the intervention group, mouthwash (disinfection cheeks, gums, palate, tongue and teeth) every 8 hours with 10 ml of ready solution of 0.2% chlorhexidine is performed by the applica
Prevention
In the control group, mouthwash (disinfection cheeks, gums, palate, tongue and teeth) every 8 hours with 10 ml of ready solution of 0.2% chlorhexidine is performed by the applicator for 30 second. Th
In the intervention group, mouthwash (disinfection cheeks, gums, palate, tongue and teeth) every 8 hours with 10 ml of ready solution of 0.2% chlorhexidine is performed by the applicator for 30 secon
Sponsors
Vice chancellor for research, Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion Criteria: The satisfaction of patient's attendant to participate in the study; The patient's age is more than 18 years; The patient has endotracheal tube through the mouth; The patient has not nasogastric tube; Expecting mechanical ventilation for at least 48 hours; On arrival to the ICU lung infiltration on chest radiograph Does not exist; At least two of the three clinical criteria indicators of ventilator associated pneumonia (rectal temperature less than 35 or more than 38 degrees Celsius, leukocyte count of less than 4,000 or more than 12,000 per cubic millimeter of blood and purulent tracheal secretions) does not exist. Exclusion criteria: desire to continue participation in the study; Allergic reaction to chlorhexidine; Clear aspiration; At least two of the three clinical criteria indicators of ventilator associated pneumonia exist in the first or second day of mechanical ventilation
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amount of Body Temperature. Timepoint: up to Five Days after beginning of Intervention. Method of measurement: By Glass Thermometer for Axillary in Degrees Celsius.;Amount of Tracheal secretions. Timepoint: up to Five Days after beginning of Intervention. Method of measurement: Based on The Required Frequency of Tracheal Suctioning.;Kind of Tracheal secretions. Timepoint: up to Five Days after beginning of Intervention. Method of measurement: On the basis of color, odor and secretions concentration and according to the nurse caring for the patient.;Amount of Blood leukocytes. Timepoint: up to Five Days after beginning of Intervention. Method of measurement: By blood test.;Ratio of Arterial Oxygenation. Timepoint: up to Five Days after beginning of Intervention. Method of measurement: By Analyze of Arterial Blood Gases.;Changes of Chest radiographic. Timepoint: up to Five Days after beginning of Intervention. Method of measurement: By the removable radiological devices (portable).;Culture of tracheal secretions. Timepoint: up to Five Days after beginning of Intervention. Method of measurement: Quantitative culture with Gram stain. | — |
Secondary
| Measure | Time frame |
|---|---|
| Ventilator associated Pneumonia. Timepoint: Up to five days after beginning of intervention. Method of measurement: By Clinical Pulmonary Infection Score.;The relationship between clinical criteria and diagnosis of pneumonia. Timepoint: Up to five days after beginning of intervention. Method of measurement: By Clinical Pulmonary Infection Score. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahdi Alimi
Mashhad University of Medical Sciences
Outcome results
None listed