burn. Burn and corrosion
Conditions
Interventions
Intervention 1: The first intervention group will receive 1800 mg Gabapentin orally 2 hours before entering the operating room. Intervention 2: In the second intervention group ketamine in the form o
Treatment - Drugs
The first intervention group will receive 1800 mg Gabapentin orally 2 hours before entering the operating room.
In the second intervention group ketamine in the form of intravenous in amount of 0.1 to 0.5 mg per kg of body weight will be given one minute before the start of surgery.
The third intervention group will receive Dexmedetomidine drug in the form of intravenous infusionand 0.1 to 0.5 mg per kilogram of body weight per minute in ten minutes before the start of surgery
In the fourth intervention group five minutes before the start of surgery,Nitrous Oxide mixed with70% oxygen through a face mask is prescribed.
Sponsors
Vice chancellor for research, Kermanshah University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age between 18 and 60 years; Burn with grade 2 and 3, burns 20 percent to 50 percent; AS A Class 1 and 2 Exclusion criteria: pregnant women; People with any known chronic mental illness; Patients with history of chronic underlying cardiac, lung and kidney disease; patients treated with certain medications such as immunosuppressive medications or chemotherapy or Corticosteroid
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amount of pain. Timepoint: Beginning of the study, half an hour, an hour, two hours, four hours, six hours after start of surgery. Method of measurement: Using visual analogue scale (VAS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSimin Chaghazardi
Kermanshah University of Medical Sciences
Outcome results
None listed