Evaluation of the effect of HFNC use in COPD patients

Evaluation of the effect of using high flow oxygen delivery through nasal cannula (HFNC) with different currents, in improving the respiratory symptoms of patients with chronic obstructive pulmonary disease (COPD) referred to Masih Daneshvari Hospital

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160516027929N9

Enrollment

Registered

2021-03-19

Start date

2021-03-21

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic obstructive pulmonary disease. chronic obstructive pulmonary disease

Interventions

Intervention 1: First intervention group: In this group, patients receive oxygen therapy through a high-flow device. The patient's transport oxygen flow is set to 30. The inlet air temperature is set

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Signing a written consent form No intubation Hypoxemic respiratory distress

Exclusion criteria

Exclusion criteria: PaCO2> 65 pH < 7.28 Age less than 18 years Cardiovascular disorders that prevent respiratory rehabilitation Diagnosis of medical staff based on the patient's absence from participating in this study

Design outcomes

Secondary

Measure	Time frame
Borg scale. Timepoint: Before starting oxygen therapy, 24 hours later. Method of measurement: Questionnaire review.;CAT score. Timepoint: Before starting oxygen therapy, 24 hours later. Method of measurement: Questionnaire review.	—

Primary

Measure	Time frame
Forced expiratory volume in first second. Timepoint: Before starting oxygen therapy, 24 hours later. Method of measurement: Spirometry.;Oxygen saturation. Timepoint: Before starting oxygen therapy, 24 hours later. Method of measurement: Pulse oximetry.;Forced vital capacity. Timepoint: Before starting oxygen therapy, 24 hours later. Method of measurement: Spirometry.;Partial pressure of carbon dioxide. Timepoint: Before starting oxygen therapy, 24 hours later. Method of measurement: VBG analysis.	—

Measure

Time frame

Forced expiratory volume in first second. Timepoint: Before starting oxygen therapy, 24 hours later. Method of measurement: Spirometry.;Oxygen saturation. Timepoint: Before starting oxygen therapy, 24 hours later. Method of measurement: Pulse oximetry.;Forced vital capacity. Timepoint: Before starting oxygen therapy, 24 hours later. Method of measurement: Spirometry.;Partial pressure of carbon dioxide. Timepoint: Before starting oxygen therapy, 24 hours later. Method of measurement: VBG analysis.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtefeh Fakharian

Shahid Beheshti University of Medical Sciences

fakharian_2005@yahoo.com+98 21 2610 5050

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026