Chronic obstructive pulmonary disease (COPD). Chronic obstructive pulmonary disease with (acute) exacerbation
Conditions
Interventions
Intervention 1: Intervention group: Intervention group: First, ABG will be measured and then HFNT will be performed and after 1 hour, ABG will be measured again. Then 30 minutes will be passed without
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: The presence of chronic obstructive pulmonary disease (COPD) and acute respiratory failure pH < 7.35 Arterial pressure of carbon dioxide (PaCO2) equal to or greater than 45mmHg
Exclusion criteria
Exclusion criteria: - Mechanical ventilation in the past 60 days (using any non-invasive ventilation or high blood oxygen through the nasal cannula (HFNT) prior to enrollment in the study and after the onset of acute upper respiratory failure (AHRF) - Non-invasive ventilation for home care - Undesirable clinical condition (require a vasopressor for> 24 hours, acute coronary syndrome or life-threatening arrhythmias ( - Refusal of treatment - Disorder in more than two organs -Heart failure - The respiratory tract requires a tracheal intubation - Trauma or burn in the neck and face - Pregnancy - Refusal of consent - enter to other research protocols
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PaCO2. Timepoint: before intervention- one hour after - half hour after- after intervention. Method of measurement: ABG. | — |
Secondary
| Measure | Time frame |
|---|---|
| SaO2. Timepoint: befor intervention-one hour after-half hour after- after intervention. Method of measurement: ABG. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAtefeh Fakharian
Shahid Beheshti University of Medical Sciences
Outcome results
None listed