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Comparison of the efficacy and side effects of desloratadine with fexofenadine on allergic rhinitis in patients referred to Masih Daneshvari Hospital

Comparison of the efficacy and side effects of desloratadine with fexofenadine on allergic rhinitis in patients referred to Masih Daneshvari Hospital

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160516027929N11
Enrollment
65
Registered
2021-09-25
Start date
2021-04-04
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic rhinitis. Allergic rhinitis due to pollen

Interventions

Intervention 1: Intervention group: In the first group, patients receive 5 mg of desloratadine daily for 4 weeks.After 2 weeks of no drug treatment, they are treated with fexofenadine 120 mg daily for

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 12 years History of allergic rhinitis or diagnosis at first visit Written consent to participate in the study

Exclusion criteria

Exclusion criteria: Sensitivity, allergy or adverse reaction to desloratadine and fexofenadine Patients who have previously been treated with two or more drugs pregnancy and breastfeeding

Design outcomes

Primary

MeasureTime frame
General clinical symptoms. Timepoint: Before starting treatment and 10 weeks after starting treatment. Method of measurement: Rhinitis Quality of Life Questionnaire.;The severity of eye symptoms. Timepoint: Rhinitis Quality of Life Questionnaire. Method of measurement: Rhinitis Quality of Life Questionnaire.;Severe itching in the nose. Timepoint: Rhinitis Quality of Life Questionnaire. Method of measurement: Rhinitis Quality of Life Questionnaire.;Sleep disorders. Timepoint: Rhinitis Quality of Life Questionnaire. Method of measurement: Rhinitis Quality of Life Questionnaire.

Secondary

MeasureTime frame
Evaluation of the clinical symptoms of allergic rhinitis. Timepoint: Before starting treatment and 10 weeks after starting treatment. Method of measurement: Physical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtefeh Fakharian

Shahid Beheshti University of Medical Sciences

fakharian_2005@yahoo.com+98 21 2610 5050

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026