Propofol Injection Pain. Parenteral anesthetics
Conditions
Interventions
Intervention 1: 20 mg Ketamine before injection of Propofol. Intervention 2: 4 mg Ondansetron before injection of Propofol. Intervention 3: 20 mg Lidocain before injection of Propofol.
Prevention
20 mg Ketamine before injection of Propofol
4 mg Ondansetron before injection of Propofol
20 mg Lidocain before injection of Propofol
Sponsors
Vice-Chancellor of Research Babol University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 18 to 60 year old ; ASA class 1 or 2 ; candidate for general anesthesia Exclusion criteria: pain at the injection site before injection of study drugs or propofol ; sensitivity to each of study drugs ; anxiety ; lack of cooperation ; history of seizure ; history of cardiovascular disease ; history of psychiatric disorders
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Degree of pain. Timepoint: seconds: 0, 30 and 60. Method of measurement: VAS. | — |
Secondary
| Measure | Time frame |
|---|---|
| Bradycardia. Timepoint: Before propofol injection,1min after propofol injection,immediately before and after intubation,5,10 and 15 min after intubation. Method of measurement: Before propofol injection,1min after propofol injection, immediately before and after intubation, 5,10 and 15 min after intubation.;Hypotension. Timepoint: Before propofol injection, 1min after propofol injection, immediately before and after intubation, 5, 10 and 15 min after intubation. Method of measurement: Before propofol injection, 1min after propofol injection, immediately before and after intubation, 5, 10 and 15 min after intubation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Bahman Hasan Nasab
Babol University of Medical Sciences
Outcome results
None listed