injury of upper limb. Other injuries of upper limb, level unspecified
Conditions
Interventions
Intervention 1: First intervention group, 3mg/kg of Lidocaine 0.5% diluted with saline plus 4 mg of Ondansetrone with a dose of 40 ml. Intervention 2: Second intervention group, 3mg/kg of Lidocaine 0.
Treatment - Drugs
Placebo
First intervention group, 3mg/kg of Lidocaine 0.5% diluted with saline plus 4 mg of Ondansetrone with a dose of 40 ml
Second intervention group, 3mg/kg of Lidocaine 0.5% diluted with Saline plus 5.7 ml of mgso4 20% with a dose of 40 ml
In control group, 3 mg/kg of Lidocaine 0.5% diluted With Saline with a dose of 40 ml
Sponsors
Vice Chancellor for research Qazvin University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: Patients 20 to 60 years old; Elective surgery of upper extremity fracture operation; with American Society of Anesthesiologists (ASA) physical status I or II; pleasure in entrance to study. Exclusion Criteria : Patients With Sickle Cell Anemia; History of hypersensitivity to drugs used in the study; History of Raynaud's Disease; Drug Abuse History; taking Nonsteroidal anti-inflammatory drugs(NSAID) or Sildindfil within last 24 hours; more than 1.5 hour long surgery.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The timing of tourniquet pain. Timepoint: In 5, 10, 15, 20, 25 and 30 minutes intraoperation. Method of measurement: Score of pain in Visual analog scale (VAS).;Post operative pain. Timepoint: In 30 min and 2, 4 and 6 hours after opration. Method of measurement: Visual analogue Scales(VAS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Post operation analgesic. Timepoint: In 30 min and 2, 4 and 6 Hours After Opration. Method of measurement: Patient file.;Onset of sensory and motor block. Timepoint: From the start of anesthetics injection. Method of measurement: Evaluate the patient’s response to needle hitting on surgical site and griping force.;Hemodynamic variables of the block. Timepoint: In 5, 10, 15 and 30 minutes intraoperation and 30 min, 2, 4, 6 hours after operation. Method of measurement: Monitoring system.;Recovery time of sensory block after opening the tourniquet. Timepoint: Every thirty seconds to return of sense in hand. Method of measurement: Short bevel needle.;Recovery time of motor block after opening the tourniquet. Timepoint: Every thirty seconds to complete movement of wrist. Method of measurement: Movement of wrist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Shabnam Emami
Qazvin University of Medical Sciences
Outcome results
None listed