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Application of Cold Atmospheric Pressure Argon and Air Plasma to Improve the Clinical Features of the Lesions in Acne Vulgaris:Double-blind randomized clinical trial

Application of Cold Atmospheric Pressure Argon and Air Plasma to Improve the Clinical Features of the Lesions in Acne Vulgaris:Double-blind randomized clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160514027888N1
Enrollment
24
Registered
2022-09-11
Start date
2022-09-23
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne vulgaris. Acne vulgaris

Interventions

Intervention 1: First intervention group: Argon plasma. In this method, an argon plasma device manufactured by Danesh Banyan Engineering Plasma Technology Co., Ltd. is used to process acne. In this me

Sponsors

Tehran University of Medical Sciences
Lead Sponsor
Shahid Beheshti University
Collaborator

Eligibility

Sex/Gender
Female
Age
16 Years to 55 Years

Inclusion criteria

Inclusion criteria: Phototype I _ VI Fitzpatrick The number of pores = 10 in each half of the face Inflammatory lesions (papules and pustules) = 50 in the whole face and = 10 in each half of the face Non-inflammatory lesions (open and closed comedones) = 50 in the whole face and = 10 in each half of the face Maximum 4 nodules with a diameter = 1 cm in the whole face Atrophic scars = 50 in the whole face and of any type (needle, box, rolling) = 5 in each half of the face Symmetrical distribution of lesions on both sides of the face Age 16 to 55 years old Gender: Female

Exclusion criteria

Exclusion criteria: Acne conglobata Acne fulminans Secondary acne (drugs and hormones) Nodulocystic acne Acne requires systemic treatment

Design outcomes

Primary

MeasureTime frame
Pour and their size in each visit. Timepoint: Variables are measured before, immediately after, one week, two weeks, three weeks, four weeks and eight weeks after the start of treatment. Method of measurement: They are measured and recorded by the SKIN SCANNER device.;Scars and their size. Timepoint: Variables are measured before, immediately after, one week, two weeks, three weeks, four weeks and eight weeks after the start of treatment. Method of measurement: They are measured and recorded by the SKIN SCANNER device.;Inflammatory and non-inflammatory acne lesions. Timepoint: Variables are measured before, immediately after, one week, two weeks, three weeks, four weeks and eight weeks after the start of treatment. Method of measurement: They are measured and recorded by the SKIN SCANNER device.;Acne severity. Timepoint: Variables are measured before, immediately after, one week, two weeks, three weeks, four weeks and eight weeks after the start of treatment. Method of measurement: They are measured and recorded by the SKIN SCANNER device.;Examination of skin roughness. Timepoint: Variables are measured before, immediately after, one week, two weeks, three weeks, four weeks and eight weeks after the start of treatment. Method of measurement: They are measured and recorded by the SKIN SCANNER device.;Skin biometric parameters. Timepoint: Variables are measured before, immediately after, one week, two weeks, three weeks, four weeks and eight weeks after the start of treatment. Method of measurement: This item is quantitatively measured and reported by CUTOMETER and MPA 9 devices.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadreza Khani

Laser and Plasma Research Institute/ Shahid Beheshti University

m_khani@sbu.ac.ir+98 21 2990 4031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026