Comparison of effect of intravenous administration of Lidocaine-Fentanyl and lidocaine on reduction of propofol induced pain during intravenous injection

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016051215281N9

Enrollment

150

Registered

2017-01-11

Start date

2013-06-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complication of anaesthesia. Other complications of anaesthesia

Interventions

Intervention 1: control group: 5cc of normal saline 0.9%,one minute before induction dose of propofol was injected. Propofol lipuro braun Germany. Intervention 2: Interventional group: second

Treatment - Drugs

control group: 5cc of normal saline 0.9%,one minute before induction dose of propofol was injected. Propofol lipuro braun Germany

Interventional group: second group 40mg of Lidocaine +50 µg Fentanyl (diluted to 5cc), one minute before injection of induction dose of propofol. Lidocaine Iran hormone- Iran Fentanyl Abura

Interventional group: Third group 40 mg Lidocaine (diluted to 5cc), one minute before injection of induction dose of propofol

Eligibility

Sex/Gender

All

Age

15 Years to 74 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients should be 16-74 years of age, they shouldn't have any cardiovascular, autoimmune disease and diabetes. Exclusion Criteria: patients who received sedative drugs 24 hours prior to surgery, any drug allergy, neurologic and/or psychologic disease, drug addicts, pregnant women,patients requiring rapid induction of anesthesia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Effect of lidocaine on reduction of propofol induced pain. Timepoint: 1 minute after injection of propofol. Method of measurement: questionnaire and defined pain scale.;Effect of Lidocaine+Fentanyl on reduction of propofol induced pain. Timepoint: 1 minute after injection of propofol. Method of measurement: Questionnaire and defined pain scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Seyed Ebrahim Sadeghi

Shiraz University of Medical Sciences

esadeghi@sums.ac.ir+98 71 4333 3278

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026