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The effect of oxytocin hormone on impulsivity and risky decision-making with regard to the genetic variants

Evaluation of the effect of oxytocin on impulsivity and risky decision-making with regard to the oxytocin receptor gene (OXTR) among healthy young males

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016051127842N1
Enrollment
160
Registered
2016-08-12
Start date
2016-10-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Impulsivity and decision making in healthy adults. -

Interventions

Intervention 1: Intervention group: healthy young men who will be selected based on inclusion criteria and will receive oxytocin nasal spray just once in a dose of 24 units. Oxytocin will be bought f
Treatment - Drugs
Placebo
Intervention group: healthy young men who will be selected based on inclusion criteria and will receive oxytocin nasal spray just once in a dose of 24 units. Oxytocin will be bought from Novartis Pha
Control group: This group includes healthy young men who will be selected based on inclusion criteria and will receive placebo just once.

Sponsors

Vice Chancellor for research of Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 28 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Perfect consciousness; being in the defined age range; Being a university student; Being male; Lack of mental disorder or neurological illness; Fill out the consent form. Exclusion criteria: being outside the defined age range; Being female; existence of mental disorders or neurological or hormonal problems or a history of them; Lack of adequate understanding of the process of project

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Impulsivity. Timepoint: Before the intervention, About 45-60 min after the intervention. Method of measurement: Go/No go task.;Risky decision making. Timepoint: Before intervention, About 45-60 min after the intervention. Method of measurement: IOWA Gambling task.;Oxytocin receptor gene variant. Timepoint: Before beginning the study. Method of measurement: PCR-RFLP Method.

Secondary

MeasureTime frame
-. Timepoint: -. Method of measurement: -.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Shahbazi

Iran University of Medical Sciences

shahbazial@yahoo.com+98 21 8862 2578

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026