Comparison effect of intravenous Vasopressin versus Norepinephrine on correction of cardiac function and renal function in low cardiac out put patient after CABG in Mosavi hospital at 1394

Effect of intravenous Vasopressin versus Norepinephrine on correction of cardiac function and renal function in low cardiac out put patient

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016051023760N2

Enrollment

Registered

2017-04-05

Start date

2016-01-09

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease. Atherosclerotic heart disease

Interventions

Intervention 1: Intrvention group1:Vasopressin Start infusion of vasopressin0.3µg/kg at off pump time and continu to end of surgery. Intervention 2: Intervention group2:Norepinephrine Infusion of No

Treatment - Drugs

Intrvention group1:Vasopressin Start infusion of vasopressin0.3µg/kg at off pump time and continu to end of surgery

Intervention group2:Norepinephrine Infusion of Norepinephrine at off pump time and continue until end of surgery

Eligibility

Sex/Gender

All

Age

30 Years to 90 Years

Inclusion criteria

Inclusion criteria: Inclusioncriteria:age 30yr and more;cardiac output more than 30%;ASA class1 Exclusion criteria:severe cardiac arrhithmia;heart faliure;cardiogenic shock;unstable hemodynamic;diabet mellitus;pulmonary disease;vascular disease;pulmonary HTN;pathologic change of liver;emergency CABG

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Lelft Ventricular Contraction. Timepoint: Before intervention and 4 days afeter intervention. Method of measurement: Echocardiography.;Mean Arterial Pressure. Timepoint: Before surgery ,Before CPB,During CPB,After CPB and before transer to ICU. Method of measurement: Invasive Blood Pressure Monitoring.;Serum Creatinin. Timepoint: Before surgery and before transer to ICU. Method of measurement: Laboratory Elisa kit.;Volume of Hemorrage. Timepoint: End of surgery and every 6 houre until 24 houres after end of surgery. Method of measurement: Mililiter.;BUN. Timepoint: Before surgery and before transer to ICU. Method of measurement: Laboratory Elisa kit.	—

Measure

Time frame

Lelft Ventricular Contraction. Timepoint: Before intervention and 4 days afeter intervention. Method of measurement: Echocardiography.;Mean Arterial Pressure. Timepoint: Before surgery ,Before CPB,During CPB,After CPB and before transer to ICU. Method of measurement: Invasive Blood Pressure Monitoring.;Serum Creatinin. Timepoint: Before surgery and before transer to ICU. Method of measurement: Laboratory Elisa kit.;Volume of Hemorrage. Timepoint: End of surgery and every 6 houre until 24 houres after end of surgery. Method of measurement: Mililiter.;BUN. Timepoint: Before surgery and before transer to ICU. Method of measurement: Laboratory Elisa kit.

—

Countries

Iran (Islamic Republic of)

Contacts

Public Contact?Dr.Robab Azizi

Zanjan University of Medical Siences

robabazizi60@gmail.com+98 24 3313 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026