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tDCS Effects on Aphasia and Executive Function

Evaluation of the Efficacy of Transcranial Direct Current Stimulation (tDCS) on Aphasia Severity and Executive Function in Individuals with Chronic Aphasia"

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160509027820N3
Enrollment
18
Registered
2025-08-02
Start date
2025-10-07
Completion date
Unknown
Last updated
2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aphasia. Aphasia

Interventions

Intervention 1: Intervention group: Participants in this group will first undergo a course of real transcranial direct current stimulation (tDCS), consisting of 5 consecutive sessions (one session per

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 85 Years

Inclusion criteria

Inclusion criteria: Participants must be monolingual Persian speakers, or if bilingual, Persian must be their dominant language At least six months must have passed since their stroke Right-handed based on the Edinburgh Handedness Inventory Left-hemisphere brain lesion confirmed by CT or MRI report No history of neurological diseases, epilepsy, dementia, or psychiatric disorders based on medical record review No severe dysarthria based on the evaluation by a speech and language pathologist Based on oral and verbal apraxia test results, participants must not have moderate to severe oral or speech apraxia No history of more than one stroke

Exclusion criteria

Exclusion criteria: Participants who, for any reason, choose to withdraw from further participation in the study Severe fatigue or illness preventing the individual from continuing the assessment or therapeutic procedure

Design outcomes

Primary

MeasureTime frame
Aphasia severity score based on the P-WAB test. Timepoint: Prior to the intervention, 5 days post real/sham stimulation, 7 days post washout period, and 5 days post real/sham stimulation. Method of measurement: The severity of aphasia is determined based on the Aphasia Quotient (ranging from 0 to 100), which is categorized into very severe, severe, moderate, and mild levels.;Executive function indices. Timepoint: Prior to the intervention, 5 days post real/sham stimulation, 7 days post washout period, and 5 days post real/sham stimulation. Method of measurement: Determination of the score derived from the administration of the Wisconsin Card Sorting Test.;Memory indices. Timepoint: Prior to the intervention, 5 days post real/sham stimulation, 7 days post washout period, and 5 days post real/sham stimulation. Method of measurement: Determination of the score obtained from the administration of the Wechsler Memory Test-Third Edition.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBahareh Rezaei

Hamedan University of Medical Sciences

rezaeibahareh@yahoo.com+98 81 3824 0987

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026