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The IV Ondansetron on analgesic effects of IV Acetaminophen after pediatric tonsillectomy

The effect of IV Ondansetron on analgesic effects of IV Acetaminophen after pediatric tonsillectomy: a double blinded randomized clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160508027793N1
Enrollment
60
Registered
2019-09-12
Start date
2019-08-15
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic tonsillitis and adenoiditis. Chronic tonsillitis and adenoiditis

Interventions

Intervention 1: Intervention group: Intravenous ondansetron 0.1 mg / kg in 2 ml volume plus intravenous acetaminophen 15 mg / kg 15 minutes before surgery and acetaminophen suppository every 6 hours t

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 12 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria :• Age 4-5 years: Candidate for elective adenotonsillectomy • Parental consent• • No history of psychiatric illness • Do not use the apparatus 2 hours before surgery • Insensitivity to ondansetron or acetaminophen • No history of venous hepatic disease

Exclusion criteria

Exclusion criteria: • Failure to cooperate after initial interventions • Failure to show proper pain level • The patient has a decreased level of consciousness.

Design outcomes

Primary

MeasureTime frame
Painless. Timepoint: 15 minutes before surgery and every 6 hours to 24 hours. Method of measurement: Children's hospital Eastern Ontario Pain Scale (ChEOPS).

Secondary

MeasureTime frame
Nausea and vomiting. Timepoint: Four times at recovery, 6 hours, 12 hours and 24 hours after surgery. Method of measurement: ask.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLeyla Halimi

Hamedan University of Medical Sciences

lhhalimi20@yahoo.com+98 81 3838 0032

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026