Hypertension. Essential (primary) hypertension
Conditions
Interventions
Group A receives 30 grams of powdered flaxseed by eating 90 gram bread daily for 14 weeks
Group B receives 30 grams of of powdered sesame by eating 90 gram bread daily for 14 weeks
Intervention 1: Group A receives 30 grams of powdered flaxseed by eating 90 gram bread daily for 14 weeks. Intervention 2: Group B receives 30 grams of of powdered sesame by eating 90 gram bread daily
Treatment - Other
Sponsors
Vice Chancellor for Research and Technology of Shahid Sadoughi University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age between 30 to 65 years; stage I hypertension (Systolic Blood Pressure (SBP) 140-159 mmHg, Diastolic Blood Pressure (DBP) 90-99 mmHg); using a particular anti-hypertensive therapy for at least 3 months; cholesterol less than 240 mg/dl. Exclusion Criteria: pregnant women or women planning to get pregnant; being allergic to sesame or flaxseed; suffering from intestinal diseases such as Crohn's disease, colitis, peptic ulcer, irritable bowel syndrome (IBS), and other severe systemic diseases such as systemic lupus erythematosus (SLE), cancer, or stage IV respiratory diseases; history of myocardial infarction; coronary bypass surgery during last 6 months; stage II hypertension; diabetes; routinely using nonsteroidal anti-inflammatory drugs (NSAID's); change of anti-hypertensive drugs during the study; using drugs for hyperlipidemia
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Free radical scavenging capacity. Timepoint: prior to study, Seventh week, and at the end of study. Method of measurement: this is showed in % and is obtained by measuring DPPH (1,1-diphenyl-2-picryl hydrazyl radical). This measurement is done by Elisa.;Malondialdehyde (MDA). Timepoint: prior to study, Seventh week, and at the end of study. Method of measurement: micromol/L; it is measured by Elisa.;Cholesterol. Timepoint: prior to study, Seventh week, and at the end of study. Method of measurement: mg/dL.;Triglyceride. Timepoint: prior to study, Seventh week, and at the end of study. Method of measurement: mg/dL.;Low density lipoprotein (LDL). Timepoint: prior to study, Seventh week, and at the end of study. Method of measurement: mg/dL.;High density lipoprotein (HDL). Timepoint: prior to study, Seventh week, and at the end of study. Method of measurement: mg/dL. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMoneyreh Modares Mosadegh
Shahid Sadoughi University of Medical Sciences
Outcome results
None listed