Zinc supplement effect in treatment of the children with attention deficiency-hyperactivity disorder (ADHD)

Evaluating effect of the zinc as a supplement to methylphenidate in children suffering ADHD

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016050716077N5

Enrollment

Registered

2016-05-22

Start date

2013-04-04

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Attention deficiency-hyperactivity disorder. Disturbance of activity and attention

Interventions

Intervention 1: Group B: Methylphenidate tablet in 0.5 to 1 mg/kg/day doses accompanied by 10 milliliter zinc sulfate syrup for 6 weeks. Intervention 2: Group A: Methylphenidate tablet in 0.5 to 1 mg/

Treatment - Drugs

Group B: Methylphenidate tablet in 0.5 to 1 mg/kg/day doses accompanied by 10 milliliter zinc sulfate syrup for 6 weeks

Group A: Methylphenidate tablet in 0.5 to 1 mg/kg/day doses accompanied with placebo for 6 weeks

Eligibility

Sex/Gender

All

Age

7 Years to 12 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: children aged between 7 to 12 years; ADHD diagnosis made by youth and children psychiatry subspecialist according to DSM-IV criteria and approved by K-SADS form; no prohibition to consumption of the zinc supplements such as copper consumption; IQ more than 70; without any other psychiatric disorders approved by K-SADS form; no history of zinc consumption during last two months; receiving methylphenidate tablet in 0.5 to 1 mg/kg/day doses as treatment Exclusion criteria: cancelling participation by parents or child consciously; not consuming according to the prescription; change in treatment method; interrupting treatment due to any reason such as drug adverse effects

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Determining symptoms severity improvement in each group according to the Kanerz questionnaire scores. Timepoint: After intervention. Method of measurement: Using Kanerz parents and teachers questionnaire.	—

Secondary

Measure	Time frame
Determining zinc supplement effect on hyperactivity score improvement in Kanerz questionnaire. Timepoint: Before intervention, after intervention. Method of measurement: Using Kanerz parents and teachers questionnaire.;Determining zinc supplement effect on inattention score improvement in Kanerz questionnaire. Timepoint: Before intervention, after intervention. Method of measurement: Using Kanerz parents and teachers questionnaire.;Determining zinc supplement effect on hyperactivity score impulsivity in Kanerz questionnaire. Timepoint: Before intervention, after intervention. Method of measurement: Using Kanerz parents and teachers questionnaire.	—

Measure

Time frame

Determining zinc supplement effect on hyperactivity score improvement in Kanerz questionnaire. Timepoint: Before intervention, after intervention. Method of measurement: Using Kanerz parents and teachers questionnaire.;Determining zinc supplement effect on inattention score improvement in Kanerz questionnaire. Timepoint: Before intervention, after intervention. Method of measurement: Using Kanerz parents and teachers questionnaire.;Determining zinc supplement effect on hyperactivity score impulsivity in Kanerz questionnaire. Timepoint: Before intervention, after intervention. Method of measurement: Using Kanerz parents and teachers questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Seyed Gholamreza Nour Azar

Tabriz University of Medical Sciences

Noorazars@tbzmed.ac.ir+98 41 3334 1705

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026