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Effect of aluminum chloride hexahydrate gel iontophoresis on hyperhidrosis

Comparative evaluation of iontophoresis with aluminum chloride hexahydrate gel versus iontophoresis with Tap water in people with primary palmar hyperhidrosis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160506027762N2
Enrollment
32
Registered
2020-02-09
Start date
2018-01-21
Completion date
Unknown
Last updated
2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Palmar hyperhidrosis.

Interventions

Intervention 1: Intervention group:16 patients with Palmar hyperhidrosis will receive iontophoresis with aluminum chloride hexahydrate gel ( manufactured in department of pharmaceutical of Shahid Be

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Age 18-40, BMI 17-30.presence of focal, visible sweating for at least 6 months without any obvious cause, besides the presence of at least two of the following characteristics: Bilateral and relatively symmetrical sweating, frequency of at least one episode per week, impairment of daily activities of the patient, age of onset less than 25 years, a positive family history and cessation of focal sweating during sleep. HDSS 2 or 3 .

Exclusion criteria

Exclusion criteria: Having pacemaker or substantial metal implants located in electrical current path, being pregnant, suffering from systemic disease leading to hyperhidrosis and any central or peripheral nervous system diseases. SSR (sympathetic skin response) greater than normal or absent SSR

Design outcomes

Primary

MeasureTime frame
Sweating rate. Timepoint: before and 3 days, 1, 2, 3, 4, 8 weeks, and 24 weeks after the last treatment session. Method of measurement: Sweating rate with gravimetry test.;Quality of Life score in DLQI questionnaire. Timepoint: before and 3 days, 1, 2, 3, 4, 8 weeks, and 24 weeks after the last treatment session. Method of measurement: Quality of Life score with DLQI questionnaire.

Secondary

MeasureTime frame
Sympathetic Skin Response (SSR). Timepoint: Before and after the application of one session iontophoresis. Method of measurement: Using a Medelec Synergy Electromyography instrument.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Majid Hosseini

School of Rehabilitation, Shahid Beheshti University of medical Sciences

majidhosseini44@yahoo.com+98 21 7756 1723

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026