Palmar hyperhidrosis.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Age 18-40, BMI 17-30.presence of focal, visible sweating for at least 6 months without any obvious cause, besides the presence of at least two of the following characteristics: Bilateral and relatively symmetrical sweating, frequency of at least one episode per week, impairment of daily activities of the patient, age of onset less than 25 years, a positive family history and cessation of focal sweating during sleep. HDSS 2 or 3 .
Exclusion criteria
Exclusion criteria: Having pacemaker or substantial metal implants located in electrical current path, being pregnant, suffering from systemic disease leading to hyperhidrosis and any central or peripheral nervous system diseases. SSR (sympathetic skin response) greater than normal or absent SSR
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sweating rate. Timepoint: before and 3 days, 1, 2, 3, 4, 8 weeks, and 24 weeks after the last treatment session. Method of measurement: Sweating rate with gravimetry test.;Quality of Life score in DLQI questionnaire. Timepoint: before and 3 days, 1, 2, 3, 4, 8 weeks, and 24 weeks after the last treatment session. Method of measurement: Quality of Life score with DLQI questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Sympathetic Skin Response (SSR). Timepoint: Before and after the application of one session iontophoresis. Method of measurement: Using a Medelec Synergy Electromyography instrument. | — |
Countries
Iran (Islamic Republic of)
Contacts
School of Rehabilitation, Shahid Beheshti University of medical Sciences