REMOTE ISCHEMIC PRECONDITIONING effect in the prevention of acute kidney injury in coronary angiography

Effect of limb Ischemic Preconditioning Remote on the prevention of acute kidney injury caused by contrast agents in patients with impaired renal function

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016050222935N2

Enrollment

140

Registered

2016-12-19

Start date

2015-05-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease. Chronic kidney disease

Interventions

Intervention 1: In intervention group we inflate the blood pressure cuff up to 50 mmHg above the systolic blood pressure in the upper arm and after 5 minutes will deflate the blood pressure cuff. This

In intervention group we inflate the blood pressure cuff up to 50 mmHg above the systolic blood pressure in the upper arm and after 5 minutes will deflate the blood pressure cuff. This intervention wi

In the control group the blood pressure cuff will be inflated to 10 mmHg below the diastolic blood pressure of the patient for 5 minutes an then will be deflated for 5 minutes. This process will be do

Eligibility

Sex/Gender

All

Age

20 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria :1 age>= 20 years; renal dysfunction (cr> 1.4 mg / dl or GFR <60 ml / min); estimated contrast medium use more than 100 ml. Exclusion criteria: end stage renal disease (ESRD) requiring dialysis ; contrast medium use<70 ml

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Increase in Cystatin C>10%. Timepoint: The day before and 48 hours after angiography. Method of measurement: By assay kit.	—

Secondary

Measure	Time frame
Increase in serum creatinine level. Timepoint: before and 48-72 hr after. Method of measurement: laboratory.;Increase in cystatin C level. Timepoint: before and 48-72 hr after. Method of measurement: laboratory.;Creatinine change. Timepoint: before and 48-72 hr after. Method of measurement: laboratory.;Cystatin C change. Timepoint: before and 48-72 hr after. Method of measurement: laboratory.;Contrast induced acute kidney injury(increase in Cr>=0.3 mg/dL). Timepoint: before and 48-72 hr after. Method of measurement: laboratory.	—

Measure

Time frame

Increase in serum creatinine level. Timepoint: before and 48-72 hr after. Method of measurement: laboratory.;Increase in cystatin C level. Timepoint: before and 48-72 hr after. Method of measurement: laboratory.;Creatinine change. Timepoint: before and 48-72 hr after. Method of measurement: laboratory.;Cystatin C change. Timepoint: before and 48-72 hr after. Method of measurement: laboratory.;Contrast induced acute kidney injury(increase in Cr>=0.3 mg/dL). Timepoint: before and 48-72 hr after. Method of measurement: laboratory.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Ghaemian

Mazandaran University of Medical Sciences

aligmdc@yahoo.com+98 11 3331 4086

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 4, 2026