Effect of prophylactic fibrinogen on the need for perioperative blood transfusion in traumatic patients undergoing abdominal surgery

fibrinogen and blood requirement in trauma patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016050220795N3

Enrollment

Registered

2016-05-15

Start date

2016-05-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Injury of intra-abdominal organs. Injury of intra-abdominal organs

Interventions

Intervention 1: Ppatients in the control group will receive 30 mg/kg of fibrinogen concentrate (diluted in 100 mL of distilled water) within 10 minutes. Intervention 2: Control group: No intervention

Treatment - Drugs

Ppatients in the control group will receive 30 mg/kg of fibrinogen concentrate (diluted in 100 mL of distilled water) within 10 minutes.

Control group: No intervention will be made in this group.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: All trauma patients. Exclusion criteria: Patients having received fibrinogen or cryoprecipitate before operation, Patients with hereditary or acquired coagulopathies and history of allergy to fibrinogen concentrate.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Transfusion requirements. Timepoint: Before and after surgery. Method of measurement: Hemoglobin levels.	—

Secondary

Measure	Time frame
Fibrinogen plasma level. Timepoint: Before and after surgery. Method of measurement: fibrinogen plasma level.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSamad Eslam Jamal Golzari

Tabriz University of Medical Sciences

golzaris@tbzmed.ac.ir+98 41 3334 7054

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026