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Evaluation of the Response to Treatment of HIV-1 Infected Men's Semen Sperm Washing Method in Pregnancy of Sero-Discordant Couples

Evaluation of the Response to Treatment of HIV-1 Infected Men's Semen Sperm Washing Method in Pregnancy of Sero-Discordant Couples who Referred to Behavioral Diseases Consultation Center

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201604304076N19
Enrollment
15
Registered
2016-06-27
Start date
2016-04-03
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: HIV/AIDS. Condition 2: Pregnancy, childbirth and the puerperium. Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases Delivery by caesarean section, unspecified

Interventions

Intervention 1: Intervention group: In this method, healthy and motile uninfected sperm cells are isolated from other cells. Semen samples will be loaded on a sperm washing medium gradient and then ce
Prevention
Intervention group: In this method, healthy and motile uninfected sperm cells are isolated from other cells. Semen samples will be loaded on a sperm washing medium gradient and then centrifuged. Final
Control group: This study is a single arm clinical trial that has no control group.

Sponsors

Resaerch Deputy of Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: Inclusion criteria: Being Married; Men who living with HIV-1; The consent of both spouses; Uninfected women. Exclusion criteria: Lack of consent; Serum Viral load of over 500 RNA copy number/ ml.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Mother infection status. Timepoint: Before the first-trimester, second-trimester and third-trimester of pregnancy. Method of measurement: Laboratory tests.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Minoo Mohraz

Iranian research Center for HIV AIDS (IRCHA)

ircha@tums.ac.ir+98 21 6694 7984

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026