Effect of Granisetron on pruritus

Comparison the effect of intravenous Granisetron and placebo on pruritus after intrathecal opioid in cesarean section with spinal anesthesia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016043027677N1

Enrollment

136

Registered

2016-06-20

Start date

2015-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

opioid induced pruritus. Itch NOS

Interventions

Intervention 1: Immediately after clamping the umbilical cord for study group granisetron ( pharmaceutical company Caspian ) 1 mg by intravenous injected. Intervention 2: immediately after clamping th

Treatment - Drugs

Immediately after clamping the umbilical cord for study group granisetron ( pharmaceutical company Caspian ) 1 mg by intravenous injected

immediately after clamping the umbilical cord in the same volume of saline in the control group were injected intravenously

Eligibility

Sex/Gender

Female

Age

76 Years to 96 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria were not a history of gastrointestinal disease? allergies to medications? pre-eclampsia? eclampsia was taken into account.Exclusion criteria was people who have used anti-nausea drug in the last 24 hours.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pruritus. Timepoint: During the surgery and ricovery. Method of measurement: Visual Analog Scale.	—

Secondary

Measure	Time frame
Nausea and vomiting. Timepoint: During surgery and recovery room. Method of measurement: Has- does not have.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahryar Sane

Urmia University of Medical Sciences

sane.sh@umsu.ac.ir; shahryarsane@yahoo.com; dr.sh.sane@gmail.com+98 44 3193 7000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026