Pain. Pain in arm, unspecified
Conditions
Interventions
Intervention 1: Intervention group will be received Melatonin LLC USA Melatonin, Nature Made/Pharmative 6 mg tablet oral placebo 90 minutes before surgery. Intervention 2: Control group will be rec
Sponsors
Oroumia University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients aged 20-60 years Patients with American Society of Anesthesiologists (ASA) physical status classification I–II Elective upper limb surgery Surgery with intravenous regional anesthesia
Exclusion criteria
Exclusion criteria: Raynaud’s disease Sickle cell anemia Chronic pain syndromes Depression or schizophrenia Epilepsy Leukemia Autoimmune disease Diabetes Those who used any analgesic or sedative 24h before surgery Those with allergy to any of the study medications Pregnants Breast-feeding women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: Immediately after filling the tourniquet and in minutes 10, 20, 30, 40 and 50 during the surgery. Method of measurement: Verbal Pain Score.;Anxiety. Timepoint: Immediately after filling the tourniquet and in minutes 10, 20, 30, 40 and 50 during the surgery. Method of measurement: Verbal Anxiety Score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean arterial pressure. Timepoint: Immediately after filling the tourniquet and in minutes 10, 20, 30, 40 and 50 during the surgery. Method of measurement: None invasive barometer pressure.;Heart rate. Timepoint: Immediately after filling the tourniquet and in minutes 10, 20, 30, 40 and 50 during the surgery. Method of measurement: Electrocardiogram.;Arterial oxygen saturation. Timepoint: Immediately after filling the tourniquet and in minutes 10, 20, 30, 40 and 50 during the surgery. Method of measurement: Pulse oximeter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShahryar Sane
Oroumia University of Medical Sciences
Outcome results
None listed