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Clinical trial the effect of local Dexmedetomidine injection on post operative pain in patient with total knee arthroplasty surgery

Evaluation the effect of local Dexmedetomidine injection on post operative pain in total knee arthroplasty surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160430027677N7
Enrollment
12
Registered
2018-01-05
Start date
2017-05-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post operative pain. Complex regional pain syndrome I of unspecified lower limb

Interventions

Intervention 1: Intervention group: The study group will be received dexmedetomidine 1 micg/kg of body weight for dexamethasone. Intervention 2: Control group: will be received 25 milliliter isotonic
Treatment - Drugs
Placebo
Intervention group: The study group will be received dexmedetomidine 1 micg/kg of body weight for dexamethasone
Control group: will be received 25 milliliter isotonic saline

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patient with class I to III America society of Anesthesiologists; surgery with spinal anesthesia

Exclusion criteria

Exclusion criteria: Cardiovascular disease; Neuropathic Disease; Congenital deformity in the treated organ; Sensitivity to drugs used in the study; Arthroplasty for revision

Design outcomes

Primary

MeasureTime frame
Postoperative pain. Timepoint: In recovery, 6 and 12 hours after surgery. Method of measurement: Visual Analogue Scale.

Secondary

MeasureTime frame
The average need for an analgesic drug to control pain. Timepoint: In 12 hours after surgery. Method of measurement: milligram.;The first time to apply for post-operative pain control. Timepoint: In 12 hours after surgery. Method of measurement: hour.;Postoperative bleeding is to 12 hours. Timepoint: In 12 hours after surgery. Method of measurement: Based on the amount of blood in the Hamovak donor, it is determined in 24 hours and the amount of hemoglobin in the postoperative patients.;Sleep disorder after surgery. Timepoint: In 24hours after surgery. Method of measurement: Visual Analogue Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahryar Sane

Oroumia University of Medical Sciences

sanesh@umsu.ac.ir+98 44332234897

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026