Post craniotomy pain. Acute pain
Conditions
Interventions
Intervention 1: Intervention group: patients will receive Pregabalin 300 Mg oral tablet, 90 minutes before surgery. Intervention 2: Control group: patients will receive placebo oral tablet, 90 minutes
Sponsors
Oroumia University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Being at the age of 20 to 60 years old American Society of Anesthesiologists class I and II Being candidate for elective craniotomy
Exclusion criteria
Exclusion criteria: History of congenital mental retardation or mental disorders Pregnancy or breastfeeding History of systemic malignant tumor Previous treatment using this protocol or participation in another experimental study within the last 30 days Allergy to the drugs used in the study Body mass index greater than 30 Drug or alcohol addiction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: In recovery, 6, 12 and 24 hours after surgery. Method of measurement: Visual Analogue Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean Arterial Blood Pressure. Timepoint: In recovery, during Laryngoscopy, 6, 12 and 24 hours after surgery. Method of measurement: None Invasive Blood Pressure.;Mean pulse Rate. Timepoint: In recovery, during Laryngoscopy, 6, 12 and 24 hours after surgery. Method of measurement: Electrocardiogram. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShahryar Sane
Oroumia University of Medical Sciences
Outcome results
None listed