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Effect of oral pregabaline and clonidine on postoperative pain in tonsillectomy surgery with general anesthesia.

Comparison the effect of oral pregabaline and clonidine on postoperative pain in tonsillectomy surgery with general anesthesia.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160430027677N19
Enrollment
92
Registered
2020-01-24
Start date
2020-01-25
Completion date
Unknown
Last updated
2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain. Generalized pain NOS

Interventions

Intervention 1: Intervention group: patients will receive clonidine 150 Microgram oral tablet, 90 minutes before surgery. Intervention 2: Intervention group: patients will receive Pregabalin 300 Mg or

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Being at the age of 25 to 55 years old American Society of Anesthesiologists class I and II Elective tonsillectomy surgery

Exclusion criteria

Exclusion criteria: History of chronic pain Seizure alcohol consumption Drug Abuse Patients with a history of taking one or more analgesics daily A history of taking steroid medications Diabetes Mellitus

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: In recovery, 6, 12 and 24 hours after surgery. Method of measurement: Visual Analogue Scale.

Secondary

MeasureTime frame
Mean Arterial Blood Pressure. Timepoint: In recovery, during Laryngoscopy, 6, 12 and 24 hours after surgery. Method of measurement: None Invasive Blood Pressure.;Mean pulse Rate. Timepoint: In recovery, during Laryngoscopy, 6, 12 and 24 hours after surgery. Method of measurement: Electrocardiogram.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahryar Sane

Oroumia University of Medical Sciences

sanesh@umsu.ac.ir+98 44 3223 4897

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 11, 2026